The crash happened just before 11:30 a.m. at Whitaker Avenue and East Luzerne Street.
The crash, which appears to have involved multiple vehicles, was blocking two lanes of the southbound highway in Tinicum Township.
The accident reportedly happened around 10:15 a.m. on I-476 between Lansdale and Quakertown in Bucks County.
It happened around 10:30 a.m. at Cheltenham and Sycamore avenues in Cheltenham.
Officials say four people were taken to the hospital.
The crash, which involved two vehicles, happened at 16th and Callowhill streets around 9:50 a.m.
The crash happened around 6:30 a.m. on Monday after a tractor trailer overturned on County Road 540 (Telegraph Road) between Cool Run Road and Hummel Road.
Limerick police say the driver was wearing a camera and was going 106 mph on Lightcap Road when he reached a T intersection.
Hundreds in Berks County are remembering a pastor killed in a motorcycle crash.
Around 9:30 a.m., two vehicles were reportedly involved in a crash on the bridge.
Around 9 a.m., officers responded to the northeast corner of City Hall for reports of a pedestrian struck.
Police are responding to the scene of an accident involving a minivan and tractor-trailer in Northeast Philadelphia.
Around 8:30 a.m., the vehicle reportedly crashed into a beauty supply store on Hanover Street in Pemberton.
Officials say the crash happened between Exit 17: Front Street and Exit 17: Broad Street/Pattison Avenue.
Around 11:36 a.m., a crash involving a box truck, a tractor trailer, an SUV and a rollback style tow truck was reported at milepost A20 northbound near Lansdale.