By CBS3 Staff

PHILADELPHIA (CBS) — There are new concerns about the safety of vaping. Researchers have found a single e-cigarette can be harmful to the body’s blood vessels even when the vapor is entirely nicotine-free

A study at the Hospital of the University of Pennsylvania found vaping just once can change the way blood flows in a major artery that supplies blood to your legs.

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The change happened in healthy people who have never vaped or smoked before and reversed back to normal within a few minutes.

The researchers are trying to figure out the impact on people who repeatedly vape.