Motorists are being urged to plan ahead and use alternate routes when traveling in the area.
The eastbound lanes were closed from 8 p.m. Thursday until about 5 a.m. Friday from the Gettysburg Pike interchange to the Harrisburg West interchange.
Officials say the ramp at exit 326 will be closed to remove a tractor trailer hauling trash that overturned earlier this morning.
There is no word on when the road will reopen.
Streets Commissioner David J. Perri says Market Street from 18th to 21st Street will be temporarily closed on Nov. 30 from 6 a.m. – 4 p.m.
The accident reportedly occurred near West Hunting Park Avenue and Kelly Drive and involved an overturned vehicle and multiple other vehicles.
A sinkhole has closed part of a road in Gloucester Township, NJ.
PennDOT officials say the closure will be in effect in both directions near I-95 and the Cottman Avenue exit starting at approximately 5:45 p.m.
After several hours of sitting motionless on northbound I-95, traffic finally started flowing again Wednesday morning.
Beginning at 7 a.m., Kelly Drive will be closed heading northbound from Hunting Park to South Ferry Road for the removal of a tree.
A seven mile stretch will be closed in both directions from 12:01 am to 5am Sunday between Bensalem (Exit #351) and Delaware Valley (Exit #358) Sunday morning from midnight until 5 a.m.
The Pennsylvania Turnpike Commission says the road will be closed in both directions early Sunday between Willow Grove (Exit #343) and Bensalem (Exit #351).