The accident happened around 3:07 a.m. on I-95 South at Highland Avenue in Chester.
The accident happened around 11 p.m. just near the exit for 322 in Delaware County.
The snow is causing heavy traffic in the Philadelphia area.
Marva G. Wright, a 33-year-old woman from Baltimore, was killed when she lost control of her motorcycle while traveling on I-95 South.
Two crashes on I-95 South have caused major problems for the rush hour commute.