Dayton handed St. Joe’s their second straight loss on Thursday.
Steve Zack and Cleon Roberts led La Salle with 10 points apiece.
Kentucky, the preseason No. 1 that entered the Big Dance unranked, has reached the Final Four as an eight seed. The Wildcats will face Wisconsin, which upset top seed Arizona in a thriller.
By far the most unlikely Sweet 16 matchup is Dayton-Stanford. The 11 seed Flyers started Thursday’s madness by beating Ohio State 60-59.
Ronald Roberts Jr. scored 22 points and Chris Wilson added a career-high 20 as Saint Joseph’s defeated Dayton 79-53 on Tuesday night, winning its fifth straight and ending a six-game streak of Dayton’s.
Jerrell Wright led the Explorers (12-13, 4-7) with 15 points and five rebounds.
Kevin Dillard scored 23 points and Dayton won its fourth straight game, beating Saint Joseph’s 60-54 Wednesday night in Atlantic 10 Conference play.
Kevin Dillard and Josh Parker scored 16 points apiece to lead five Flyers in double figures as Dayton picked up an 87-77 win over Temple Saturday.