Fran Dougherty led Penn (7-19, 4-8) with 16 points and seven boards. Miles Jackson-Cartwright added 10 points.
Fran Dougherty had 23 points to lead Penn to a 68-60 win over Columbia Saturday night.
Miles Cartwright scored eight of his 22 points in the final 2 minutes as Pennsylvania held off Columbia 62-58 Friday night.
Billy Ragone scored his second touchdown of the day on a 7-yard run with 25 seconds remaining and Pennsylvania edged Columbia 27-20 on Saturday.
The Quakers have won 14 straight in this series and Columbia is 0-4 in 2011, but Penn head coach Al Bagnoli says they are not taking the Lions lightly.
Noruwa Agho scored 21 points and had five assists to lead Columbia to a 75-62 win over Pennsylvania on Saturday night.